substrate curcumin- β - d -glucuronide Search Results



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Curcumin-β-D-glucuronide is a major metabolite after oral intake of Curcumin in hepatic tissue and portal blood. Curcumin-β-D-glucuronide can be used for the research of colon cancer.
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Toronto Research Chemicals curcumin β d glucuronide cg
Curcumin β D Glucuronide Cg, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 91/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/substrate+curcumin-+%CE%B2+-+d+-glucuronide/Curcumin+beta-D-Glucuronide/pm29358184-29-6-18
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curcumin β d glucuronide cg - by Bioz Stars, 2026-09
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FUJIFILM β-glucuronidase helix pomatia
β Glucuronidase Helix Pomatia, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/substrate+curcumin-+%CE%B2+-+d+-glucuronide/%CE%B2+glucuronidase+helix+pomatia/pm28867734-52-34-44
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β-glucuronidase helix pomatia - by Bioz Stars, 2026-09
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FUJIFILM β-glucuronidase
β Glucuronidase, supplied by FUJIFILM, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/substrate+curcumin-+%CE%B2+-+d+-glucuronide/%CE%B2+glucuronidase/ppr0238052-49-7-13
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β-glucuronidase - by Bioz Stars, 2026-09
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Valiant Co Ltd β glucuronidase
Concentration of curcumin and its glucuronide and sulfate conjugates in plasma before and after hydrolysis with <t>β-glucuronidase</t> or sulfatase. Turmeric was administered to human volunteers (A-C), and plasma was obtained after 2 h, Mice (D-F) received turmeric extract by oral gavage or i.p. injection and serum was obtained after 30 or 20 min, respectively. Plasma or serum samples were left untreated or hydrolyzed with β-glucuronidase (β-gluc.) or sulfatase (Sulfat.) prior to extraction, and concentration of curcumin (A,D), curcumin-glucuronide (B,E), and curcumin-sulfate (C, F) was quantified using LC-SRM-MS. All values in A-C are different from each other at p<0.05 (n = 6). In D-F all values are different from each other within the oral and i.p. series, respectively, at p<0.05 (n = 5). Statistical analysis was performed using one-way ANOVA followed by Tukey multiple comparison tests of every pair. Error bars indicate SEM.
β Glucuronidase, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/substrate+curcumin-+%CE%B2+-+d+-glucuronide/%CE%B2-glucuronidase/pmc07080564-121-9-36
Average 96 stars, based on 1 article reviews
β glucuronidase - by Bioz Stars, 2026-09
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Extrasynthese SA cyanidin 3-o-glucoside
Concentration of curcumin and its glucuronide and sulfate conjugates in plasma before and after hydrolysis with <t>β-glucuronidase</t> or sulfatase. Turmeric was administered to human volunteers (A-C), and plasma was obtained after 2 h, Mice (D-F) received turmeric extract by oral gavage or i.p. injection and serum was obtained after 30 or 20 min, respectively. Plasma or serum samples were left untreated or hydrolyzed with β-glucuronidase (β-gluc.) or sulfatase (Sulfat.) prior to extraction, and concentration of curcumin (A,D), curcumin-glucuronide (B,E), and curcumin-sulfate (C, F) was quantified using LC-SRM-MS. All values in A-C are different from each other at p<0.05 (n = 6). In D-F all values are different from each other within the oral and i.p. series, respectively, at p<0.05 (n = 5). Statistical analysis was performed using one-way ANOVA followed by Tukey multiple comparison tests of every pair. Error bars indicate SEM.
Cyanidin 3 O Glucoside, supplied by Extrasynthese SA, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/substrate+curcumin-+%CE%B2+-+d+-glucuronide/cyanidin+3+o+glucoside/pmc06161174__metabolites___08___00046___s001-6-207-214
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cyanidin 3-o-glucoside - by Bioz Stars, 2026-09
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Concentration of curcumin and its glucuronide and sulfate conjugates in plasma before and after hydrolysis with β-glucuronidase or sulfatase. Turmeric was administered to human volunteers (A-C), and plasma was obtained after 2 h, Mice (D-F) received turmeric extract by oral gavage or i.p. injection and serum was obtained after 30 or 20 min, respectively. Plasma or serum samples were left untreated or hydrolyzed with β-glucuronidase (β-gluc.) or sulfatase (Sulfat.) prior to extraction, and concentration of curcumin (A,D), curcumin-glucuronide (B,E), and curcumin-sulfate (C, F) was quantified using LC-SRM-MS. All values in A-C are different from each other at p<0.05 (n = 6). In D-F all values are different from each other within the oral and i.p. series, respectively, at p<0.05 (n = 5). Statistical analysis was performed using one-way ANOVA followed by Tukey multiple comparison tests of every pair. Error bars indicate SEM.

Journal: Molecular nutrition & food research

Article Title: Incomplete hydrolysis of curcumin conjugates by β-glucuronidase: Detection of complex conjugates in plasma

doi: 10.1002/mnfr.201901037

Figure Lengend Snippet: Concentration of curcumin and its glucuronide and sulfate conjugates in plasma before and after hydrolysis with β-glucuronidase or sulfatase. Turmeric was administered to human volunteers (A-C), and plasma was obtained after 2 h, Mice (D-F) received turmeric extract by oral gavage or i.p. injection and serum was obtained after 30 or 20 min, respectively. Plasma or serum samples were left untreated or hydrolyzed with β-glucuronidase (β-gluc.) or sulfatase (Sulfat.) prior to extraction, and concentration of curcumin (A,D), curcumin-glucuronide (B,E), and curcumin-sulfate (C, F) was quantified using LC-SRM-MS. All values in A-C are different from each other at p<0.05 (n = 6). In D-F all values are different from each other within the oral and i.p. series, respectively, at p<0.05 (n = 5). Statistical analysis was performed using one-way ANOVA followed by Tukey multiple comparison tests of every pair. Error bars indicate SEM.

Article Snippet: D 6 -curcumin-sulfate was obtained from Toronto Research Chemicals. β-Glucuronidase (2742 U/mg; containing 7.3 U/mg sulfatase; cat.-no. 152284) and sulfatase (23.3 U/mg; containing >300 kU/g β-glucuronidase; cat.-no. S9626–5KU), both from Helix pomatia , were purchased from MP Biomedicals or Sigma, respectively.

Techniques: Concentration Assay, Injection

LC-MS analysis of curcumin and its conjugate metabolites in serum of mice administered a 1:1 mixture of curcumin and d6-curcumin by i.p. injection. Serum samples were (A) untreated or hydrolyzed with (B) β-glucuronidase or (C) sulfatase prior to extraction. Ion trace chromatograms were acquired using LC-SRM-MS analysis of curcumin (C), curcumin-sulfate (C-S), curcumin-glucuronide (C-G), and their respective d6-isotopologues. Analytical conditions are listed in Table 1. The numbers indicate the highest ion intensity in each trace. The first peak eluting in the C and d6-C chromatograms in (A) is derived from in-source fragmentation of the glucuronide conjugates C-G and d6C-G, respectively, cf. ref. [18].

Journal: Molecular nutrition & food research

Article Title: Incomplete hydrolysis of curcumin conjugates by β-glucuronidase: Detection of complex conjugates in plasma

doi: 10.1002/mnfr.201901037

Figure Lengend Snippet: LC-MS analysis of curcumin and its conjugate metabolites in serum of mice administered a 1:1 mixture of curcumin and d6-curcumin by i.p. injection. Serum samples were (A) untreated or hydrolyzed with (B) β-glucuronidase or (C) sulfatase prior to extraction. Ion trace chromatograms were acquired using LC-SRM-MS analysis of curcumin (C), curcumin-sulfate (C-S), curcumin-glucuronide (C-G), and their respective d6-isotopologues. Analytical conditions are listed in Table 1. The numbers indicate the highest ion intensity in each trace. The first peak eluting in the C and d6-C chromatograms in (A) is derived from in-source fragmentation of the glucuronide conjugates C-G and d6C-G, respectively, cf. ref. [18].

Article Snippet: D 6 -curcumin-sulfate was obtained from Toronto Research Chemicals. β-Glucuronidase (2742 U/mg; containing 7.3 U/mg sulfatase; cat.-no. 152284) and sulfatase (23.3 U/mg; containing >300 kU/g β-glucuronidase; cat.-no. S9626–5KU), both from Helix pomatia , were purchased from MP Biomedicals or Sigma, respectively.

Techniques: Liquid Chromatography with Mass Spectroscopy, Injection, Derivative Assay